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OptoVibronex, LLC

Non-invasive technique for biopsies of skin carcinomas

Presenter: Frederick Silver

 

Monday, March 11, 2019

Embassy Suites, Chesterbrook, Pennsylvania (directions)

 

About

 

Vibrational optical coherence tomography (VOCT) is a new technique that combines the imaging power of optical coherence tomography with the use of sound to characterize the physical properties of tissues. This technique has been developed to perform “virtual” biopsies and biomechanical measurements on normal and malignant tissues non-invasively and non-destructively.  In addition, results are obtained within 15 minutes and at less cost.

 

Cutaneous wound healing and the development of malignant skin lesions can be associated with changes in tissue stiffness. VOCT produces images of groups of cells as well as biomechanical information in three dimensions that can distinguish normal from pathological tissue. In addition, the biomechanical properties of the tissue margins can be characterized.

 

The images and the biomechanical data from measurements made on different skin lesions and carcinomas together can help plan surgical interventions and monitor the healing process of skin lesions. VOCT produces images of groups of cells as well as measurement of the tissue resonant frequency in three dimensions which assists in distinguishing normal from pathological tissue.

 

OptoVibronex has imaged and studied several types of skin lesions using VOCT to evaluate the morphology, stiffness, depth and margins of these structures. While cellular components present in skin and carcinomas have resonant frequencies in the range of 30 to 60 Hz, normal collagen has a resonant frequency in the range greater than 90 Hz. In comparison, fibrotic collagen is shown to have resonant frequencies above 150 Hz as does collagen from skin lesions.

 

The ratio of the resonant frequency squared to the tissue thickness obtained from VOCT can be used to grade the type of tissue response seen. Further studies are underway to establish the relationship between tissue stiffness and lesion morphology for cellular and fibrotic lesions based on the characteristic ratios of resonant frequency and tissue thickness.

 

 

3 Major Issues

 

  1. TBA

 

 

Program:

 

6:30 - Cocktails & Dinner (Cash bar and special 2-entree buffet menu)

7:45 - Frederick Silver, President of OptoVibronex, will deliver "Elevator" Pitch to the Group

8:00 - A Panel will address three major issues crucial to helping the Company reach the next level.

9:00 - Open discussion: members and guests

 

 


Reservation

 

Reserve your spot for this special event online now though PayPal.

Please note: You do not need a PayPal account to reserve your spot, most credit cards are accepted.

 

Available Media

Please note: All information obtained here is the property of those presenting and should not be copied or duplicated without written consent.

 

Slides

None available at this time

Audio

None available at this time

Video

None available at this time

Webcast

None available at this time

 

The webcast recording of the PCCI meeting is posted on the PCCI website a few days after the event.

Contact Info:

 

 

Our Sponsors

EisnerAmperGlaxoSmithKlineKEH Insurance Agency
New Jersey Institute of Technology
Science CenterWhite and Williams

 

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Questions or Coments?

Contact: Peter van der Kam,

peter@rxpcci.com | (610) 296-8086

 

 

 

Good Company! Good Drink! Good Food! Good Program! Good Fun!

 

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